Joint projects
Collaborative research with other groups, with shared scientific output.
Expertise & partnerships
We bring together expertise in modeling, analytical methods and biopharmaceutical characterization. These are the areas where we can collaborate.
We do not currently provide analytical services to third parties. Research collaboration proposals are welcome.
Pharmacometrics and modeling
- Physiologically based pharmacokinetic (PBPK) modeling
- Population pharmacokinetics (PopPK)
- Physiologically based biopharmaceutics modeling (PBBM)
- In silico modeling and simulation
- Prediction of physicochemical properties
Analytical and bioanalytical methods
- High-performance liquid chromatography with UV detection (HPLC-UV)
- HPLC with diode array detection (HPLC-DAD)
- Liquid chromatography–mass spectrometry (HPLC-MS and HPLC-MS/MS)
- Validation of analytical and bioanalytical methods
- Biological sample preparation
Physicochemical and biopharmaceutical characterization
- Thermodynamic and apparent solubility
- Solubility in biorelevant media
- pKa determination
- Plasma protein binding
Preclinical pharmacokinetics
- Design of pharmacokinetic studies in animals
- Plasma concentration–time profiles
- Non-compartmental and compartmental analysis
- Integration of in vivo data with PBPK models
Ways to collaborate
Co-supervision
Co-supervision of master's and PhD students in pharmacometrics and biopharmaceutics.
Internships and visits
We host researchers and students for working periods in the laboratory.
Industry partnerships
Research and development projects through UEM's institutional agreements.